Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.
Sildenafil is available in 25mg, 50mg, and 100mg strengths.
Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.
Common side effects include:
Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.
Sildenafil should not be used by those:
Inform your doctor of all medications and supplements before use. Interactions may occur with:
Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.
Sildenafil is available by prescription only in the UK.
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Less common side effects but serious effects include vision changes, hearing changes, and prolonged erections.
Drug-Drug Interactions:Inform the doctor if you are taking phenothiazine (thioridazine), anti-psychotic (lithium), antibiotic (linezolid, telithromycin, erythromycin, clarithromycin), an amino acid (tryptophan), pain killer (tramadol, ibuprofen, aspirin), anti-HIV (ritonavir, saquinavir, nelfinavir, atazanavir, amprenavir, fosamprenavir), anti-fungal (ketoconazole, itraconazole, fluconazole), anti-depressant (nefazodone), blood thinner (warfarin), impotent agents (sildenafil, tadalafil, vardenafil), calcium channel blocker (diltiazem, verapamil), anti-emetics (aprepitant), BPH agents and anti-migraine medicines.
Drug-Food Interactions:Do not take St. John’s wort (herbal supplement used to treat depression) while taking Dapoxetine. Avoid consuming grapefruit juice within 24 hours of taking Dapoxetine as it could lead to an increase in the level of Dapoxetine in the body.
Drug-Disease Interactions:Inform the doctor if you have cardiovascular/heart disease, a history of dizziness due to low blood pressure, depression, mania, bipolar disorder, schizophrenia, epilepsy/fits, bleeding or blood clotting problems, glaucoma, kidney problems, or moderate to severe liver problems.
Appropriate medical advice is required from the doctor before taking Dapoxetine. Do not take this medicine if you have had a heart attack, stroke, or life-threatening irregular heartbeat after taking depression medication.Appropriate medical advice is required for St John's wort (herbal supplement used for nerve problems).
Precipitation problemsAppropriate laboratory analysis is required for the to be put on drug.
PrecautionsThe doctor may prescribe this medicine in patients with epilepsy/fits who are taking phenothiazine (thioridazine), anti-psychotic (lithium), antibiotic (linezolid, telithromycin, erythromycin, clarithromycin), an amino acid (tryptophan), pain killer (tramadol, ibuprofen, aspirin), anti-HIV (ritonavir, saquinavir, nelfinavir, atazanavir, amprenavir), antibiotic (nefazodone), antibiotic (aprepitant), antibiotic (bismuth salts), diarrhoeic/diarrhoeal disorders, blood thinner (warfarin), impotent agents (sildenafil, tadalafil, vardenafil), calcium channel blocker (diltiazem, verapamil), anti-emetics (aprepitant), BPH agents and anti-motrin medicines.
This is not a complete list of all possible drug-drug interactions. If you have any questions, ask the doctor before taking this medicine.
Remember that this medicine is not an all-ay-all list. Always follow the doctor's instructions.
Consult with your doctorConsult with your doctor if you have any specific health concerns or if you think you may be pregnant or breast-feeding or are taking any other medicines. Do not drive or operate heavy machinery or machinery.
Do not take this medicine if you are taking monoamine oxidase (MAO) inhibitors (nortriptyline, doxazosin, methscopolamine).Do not take this medicine in children under 12 years of age.
Do not take this medicine if you are taking or have recently taken an MAO inhibitor. Also, do not take MAO inhibitors if they are used to treat major depression or are already taking MAO inhibitors.
Seek medical advice as soon as you start taking this medicine as it can cause adverse reactions if taken for the first time. If you are not sure, talk to your doctor before taking this medicine.
Sildenafil Citrate 100 mg Tablet is used to treat erectile dysfunction (impotence) in men. It increases blood flow to the penis to help men get an erection. It is also used to treat pulmonary arterial hypertension (PAH) by relaxing the blood vessels in the lungs, which reduces heart workload.
Take this medicine by mouth as directed by your doctor, usually once a day. The medicine will help you to get a hard erection when you are sexually excited.
Store at 20-25 degrees C (68-77 degrees F) and at room temperature away from moisture and heat.
Read the Patient Information Leaflet provided by your pharmacist before you start taking this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
The most common side effects of this medicine are dizziness, headache, nasal congestion, and indigestion. If these side effects become troublesome or last or go away, talk to your doctor.
If you notice any other side effects that require talk to your doctor, such as:
This is not a complete list of side effects and others may occur. If you notice other effects that are not as similar as the ones listed above, help your doctor or pharmacist make an informed decision.
If these side effects become troublesome or go away, your doctor will prescribe a lower dose.
If you are allergic to Sildenafil Citrate, or to any of the other ingredients of this medication, talk to your pharmacist before taking this medicine.
If you are pregnant or breastfeeding, tell your doctor before taking this medicine.
Sildenafil Citrate 100 mg Tablet works by relaxing the blood vessels in the penis, allowing increased blood flow into the penis, resulting in an erection. It also reduces heart workload by relaxing the blood vessels in the lungs, which reduces heart workload.
Take this medicine as directed by your doctor, usually once a day. The medicine helps you to get an erection when you are sexually excited.
Sildenafil Citrate 100 mg Tablet is a prescription medicine. You must first consult with your doctor or pharmacist before taking this medicine.If you are allergic to Sildenafil Citrate, or to any of the other ingredients of this medication, talk to your doctor or pharmacist before taking this medicine.
If you are breastfeeding, or if you are pregnant or trying to become pregnant, tell your doctor before taking this medicine.
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and not take the missed dose.
Seek emergency medical attention or contact a poison control center immediately.
Sildenafil is used to treat pulmonary arterial hypertension and to improve penile functions.
Sildenafil: Phosphodiesterase type 5 (PDE 5) inhibitors
Sildenafil works by blocking the effects of certain enzymes (PDE5) within the body which limits blood flow to the lungs and penis. As a result, it causes widening of blood vessels (arteries) supplying these organs, increases blood flow and oxygen supply and improves their functions.
Consult your doctor if you experience:
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Inform your doctor if you are breast-feeding a newborn if you are planning to breast-feeding an infant:Kou, you’re not supposed to take sildenafil by mouth, but by your doctor. In that case, your doctor will probably tell you to take it with or without food.
You can take sildenafil about 1-3 hours before you plan to have sex.
The present work is a summary, with a focus on the properties of Sildenafil and its role in pharmaceutical applications, particularly the drug-use and pharmacokinetic evaluation of Sildenafil. This study was carried out in a clinical study conducted at the Department of Pharmaceutical Sciences and Medical University in the Philippines (Pasco) between 2007 and 2010. In this study, the authors conducted a preliminary study to investigate the drug-use and pharmacokinetic profile of Sildenafil in a single dose of 100 mg, which was taken orally in a single-dose regimen. The main objectives of this study were: (1) to investigate the drug-use and pharmacokinetic profile of Sildenafil (50 mg/kg) in patients with erectile dysfunction; (2) to investigate the drug-use and pharmacokinetic profile of Sildenafil (50 mg/kg) in healthy volunteers; (3) to determine the effects of the dose of Sildenafil on the pharmacokinetics of Sildenafil in patients with erectile dysfunction. The results were compared to the results of a similar study, which used a double-blinded randomized study to evaluate the effects of dose of Sildenafil and the pharmacokinetic profile of Sildenafil. The results of this study showed that the dose of Sildenafil was significantly different from the placebo in the two groups. The drug-use and pharmacokinetic profiles of Sildenafil were well predicted by the drug-use and pharmacokinetic profiles of Sildenafil. The drug-use and pharmacokinetic profiles of Sildenafil were affected by the dose of Sildenafil. The drug-use and pharmacokinetic profiles of Sildenafil were affected by the dose of Sildenafil, which was found to be the most effective dose for Sildenafil.
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